{"id":196,"date":"2023-08-21T08:01:15","date_gmt":"2023-08-21T08:01:15","guid":{"rendered":"http:\/\/ivfathenscenter.gr\/?page_id=196"},"modified":"2024-10-10T07:30:39","modified_gmt":"2024-10-10T07:30:39","slug":"embryo-blastocyst","status":"publish","type":"page","link":"https:\/\/ivfathenscenter.gr\/en\/ivf\/embryo-blastocyst\/","title":{"rendered":"Embryo \/ Blastocyst Assisted Hatching"},"content":{"rendered":"\r\n<section class=\"title-section  with-desc\" >\r\n    <div class=\"ivf-container\">\r\n        <div class=\"page-title-wrap \">\r\n            <div>\r\n                <h1 class=\"h2 page-title\">EMBRYO \/ BLASTOCYST ASSISTED HATCHING<\/h1>\r\n                                    <div class=\"page-desc\">\r\n                        <p><p><span style=\"font-weight: 400\">The embryos&#8217; breaking out of their protective cover (Zona Pellucida) is a critical step in their development and can be assisted, if necessary, to increase chances of implantation.<\/span><\/p>\n<\/p>\r\n                    <\/div>\r\n                            <\/div>\r\n        <\/div>\r\n    <\/div>\r\n<\/section>\r\n\n\n\n<section class=\" services-content\">\n\n    \n    <div class=\"ivf-container  ivf-small-container section-content-wrap split\">\n\n                    <div class=\"image \">\n                <img loading=\"lazy\" decoding=\"async\" width=\"1000\" height=\"1000\" src=\"https:\/\/ivfathenscenter.gr\/wp-content\/uploads\/2023\/08\/embryo-blastocyst.png\" class=\"attachment-large size-large\" alt=\"\" srcset=\"https:\/\/ivfathenscenter.gr\/wp-content\/uploads\/2023\/08\/embryo-blastocyst.png 1000w, https:\/\/ivfathenscenter.gr\/wp-content\/uploads\/2023\/08\/embryo-blastocyst-300x300.png 300w, https:\/\/ivfathenscenter.gr\/wp-content\/uploads\/2023\/08\/embryo-blastocyst-150x150.png 150w, https:\/\/ivfathenscenter.gr\/wp-content\/uploads\/2023\/08\/embryo-blastocyst-768x768.png 768w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/>            <\/div>\n        \n        <div class=\"text\">\n            <p class=\"text__desc\">\n                <p><iframe loading=\"lazy\" src=\"https:\/\/www.youtube.com\/embed\/DKlQyTQt-aQ\" width=\"484\" height=\"273\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400\">Zona pellucida (ZP) protects the oocyte and the developing embryo from infections and holds the initial cells (blastomeres) together while they are still autonomous. As the embryo develops after the stage of morula, (approximately on the 4th day of development, 87-96 hours post fertilization) the blastomeres merge together and the ZP starts thinning. Following implantation the growing embryo has reached the blastocyst stage and performs ZP hatching.\u00a0<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400\">Zona pellucida degenerates and decomposes, to be replaced by the underlying layer of\u00a0<\/span><a href=\"https:\/\/en.wikipedia.org\/wiki\/Trophoblast\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400\">trophoblastic<\/span><\/a><span style=\"font-weight: 400\">\u00a0cells and the pregnancy journey begins.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400\">It is suspected that as a result of IVF techniques (multiple maturation of the follicles, medication, vitrification and warming), increased woman&#8217;s age etc, the ZP is much more solid and it is harder to hatch naturally.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400\">That is why, in IVF Athens Center in most of <\/span><span style=\"font-weight: 400\">IVF cycles we perform <\/span><span style=\"font-weight: 400\">artificial opening\u00a0 of <\/span>the zona with a technique called <span style=\"font-weight: 400;color: #b02e85\"><b>Assisted Hatching<\/b><\/span>.<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400\">The technique is not invasive or harmful, it happens under the inverted microscope using\u00a0 specific laser lenses, and is applied prior the embryo transfer either on day 3 (cleavage stage) or day 5 (blastocyst stage) of development. The same method is also used in PGT cases because the opening of the zona is absolutely necessary to remove the blastomeres for genetic testing.\u00a0\u00a0\u00a0<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400\">It has been reported in bibliography, that <\/span><span style=\"font-weight: 400;color: #b02e85\"><b>Assisted Hatching<\/b><\/span><span style=\"font-weight: 400\"> increases pregnancy rates.<\/span><\/p>\n<p>&nbsp;<\/p>\n            <\/p>\n        <\/div>\n\n        \n    <\/div>\n\n        \n<\/section>\n\n\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":6297,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-196","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/ivfathenscenter.gr\/en\/wp-json\/wp\/v2\/pages\/196","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ivfathenscenter.gr\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/ivfathenscenter.gr\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/ivfathenscenter.gr\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ivfathenscenter.gr\/en\/wp-json\/wp\/v2\/comments?post=196"}],"version-history":[{"count":27,"href":"https:\/\/ivfathenscenter.gr\/en\/wp-json\/wp\/v2\/pages\/196\/revisions"}],"predecessor-version":[{"id":6070,"href":"https:\/\/ivfathenscenter.gr\/en\/wp-json\/wp\/v2\/pages\/196\/revisions\/6070"}],"up":[{"embeddable":true,"href":"https:\/\/ivfathenscenter.gr\/en\/wp-json\/wp\/v2\/pages\/6297"}],"wp:attachment":[{"href":"https:\/\/ivfathenscenter.gr\/en\/wp-json\/wp\/v2\/media?parent=196"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}